Thermo Fisher Scientific CD13 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:100

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 668-967 of human CD13/CD13/ANPEP (NP_0011412) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD13,uniProtId:P15144-1,ncbiNodeId:9606,antigenRange:668-967,antigenLength:967,antigenImageFileName:PA5-120936_CD13_P15144-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120936_CD13_P15144-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.76 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914508

Product Specific Information

Positive test controls include: OVCAR3, Mouse kidney, Rat kidney. The target is usually found in the following locations: Cell membrane, Cytoplasm, Single-pass type II membrane protein, cytosol.

Immunogen sequence: LASAHKVPVT LALNNTLFLI EERQYMPWEA ALSSLSYFKL MFDRSEVYGP MKNYLKKQVT PLFIHFRNNT NNWREIPENL MDQYSEVNAI STACSNGVPE CEEMVSGLFK QWMENPNNNP IHPNLRSTVY CNAIAQGGEE EWDFAWEQFR NATLVNEADK LRAALACSKE LWILNRYLSY TLNPDLIRKQ DATSTIISIT NNVIGQGLVW DFVQSNWKKL FNDYGGGSFS FSNLIQAVTR RFSTEYELQQ LEQFKKDNEE TGFGSGTRAL EQALEKTKAN IKWVKENKEV VLQWFTENSK

Target Information

CD13 (ANPEP) is a 150-170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. CD13 is a metalloprotease that preferentially catalyzes removal of neutral amino acids from small peptides, thus activating or inactivating bioactive peptides. CD13 also has a role in extracellular matrix degradation, antigen processing and signal transduction, is important in inflammatory responses, regulates intercellular contact, cell motility and vascularization. CD13 is expressed by granulocytes, monocytes, myeloid leukemia cells, and is involved in protection of leukemic cells against apoptosis and its expression associated with poor prognosis of carcinomas. CD13 functions as an aminopeptidase enzyme and is also alpha receptor for coronavirus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.