Thermo Fisher Scientific CD13 Polyclonal Antibody
CD13 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA에 적합. 인간, 마우스, 랫트 반응성. 고순도 Affinity Chromatography 정제, 액상 형태로 -20°C 보관. 세포막 및 세포질 CD13 검출에 유용.
- 카탈로그번호
- PA5120936
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific CD13 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 668–967 of human CD13/ANPEP (NP_0011412) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.76 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914508 |
Product Specific Information
- Positive test controls: OVCAR3, Mouse kidney, Rat kidney
- Localization: Cell membrane, Cytoplasm, Single-pass type II membrane protein, Cytosol
Immunogen Sequence:
LASAHKVPVT LALNNTLFLI EERQYMPWEA ALSSLSYFKL MFDRSEVYGP MKNYLKKQVT PLFIHFRNNT NNWREIPENL MDQYSEVNAI STACSNGVPE CEEMVSGLFK QWMENPNNNP IHPNLRSTVY CNAIAQGGEE EWDFAWEQFR NATLVNEADK LRAALACSKE LWILNRYLSY TLNPDLIRKQ DATSTIISIT NNVIGQGLVW DFVQSNWKKL FNDYGGGSFS FSNLIQAVTR RFSTEYELQQ LEQFKKDNEE TGFGSGTRAL EQALEKTKAN IKWVKENKEV VLQWFTENSK
Target Information
CD13 (ANPEP) is a 150–170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types.
It catalyzes removal of neutral amino acids from small peptides, activating or inactivating bioactive peptides.
CD13 plays roles in:
- Extracellular matrix degradation
- Antigen processing and signal transduction
- Inflammatory response regulation
- Intercellular contact, cell motility, and vascularization
CD13 is expressed by granulocytes, monocytes, and myeloid leukemia cells, and its expression is associated with poor prognosis in carcinomas.
It also functions as an aminopeptidase enzyme and serves as an alpha receptor for coronavirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일 정보: PA5-120936_CD13_P15144-1_Rabbit.svg, PA5-120936_CD13_P15144-1_Rabbit_PDP.jpeg)
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