Thermo Fisher Scientific Epo Polyclonal Antibody
EPO 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC, ELISA에 사용 가능. Human, Mouse, Rat에 반응하며 Affinity Chromatography로 정제됨. PBS와 50% glycerol buffer에 보관하며 -20°C에서 저장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 93–193 of human EPO (NP_0007902) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.41 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914509 |
Product Specific Information
- Positive test controls: Mouse liver
- Localization: Secreted
Immunogen sequence:
GLALLSEAVL RGQALLVNSS QPWEPLQLHV DKAVSGLRSL TTLLRALGAQ KEAISPPDAA SAAPLRTITA DTFRKLFRVY SNFLRGKLKL YTGEACRTGD R
Target Information
Erythropoietin (EPO) protein is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. It induces the final maturation of partially differentiated erythroid cells and promotes production of red cell-specific proteins such as hemoglobin.
The EPO receptor (EPOR) is highly expressed on precursor cells and decreases with maturation. Hepatocytes are the main source of EPO in the fetus, while in adults, interstitial kidney cells are the primary producers. EPO expression increases under hypoxic conditions and has been detected at low levels in lung and brain tissue. Recent studies suggest EPO may also protect neuronal tissue and promote repair processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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