Thermo Fisher Scientific PSMC4 Polyclonal Antibody
Human PSMC4 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 실험에 사용 가능. 0.05 mg/mL 농도의 액상 형태이며, 항원 친화 크로마토그래피로 정제됨. 4°C 단기 보관 및 -20°C 장기 보관 권장.
- 카탈로그번호
- PA552153
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PSMC4 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PSMC4. Recombinant protein control fragment (Product #RP-102167) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646065 |
Product Specific Information
Immunogen sequence:
LTSDQKPDVM YADIGGMDIQ KQEVREAVEL PLTHFELYKQ IGIDPPRGVL MYGPPGCGKT MLAKAVAHHT TAAFIRVVGS EFVQKYLGEG PRMVRDVFRL AKENAPAIIF IDEIDAIATK RFDAQTGADR EVQRILLEL
Ortholog identity:
- Mouse: 100%
- Rat: 100%
Target Information
The 26S proteasome is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator. The 20S core consists of four rings with 28 non-identical subunits (two alpha and two beta rings). The 19S regulator includes a base (six ATPase and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and cleave peptides via an ATP/ubiquitin-dependent, non-lysosomal pathway. The immunoproteasome plays a key role in processing class I MHC peptides.
The PSMC4 gene encodes one of the ATPase subunits of the 19S regulator, belonging to the triple-A ATPase family with chaperone-like activity. It interacts with liver-expressed nuclear receptor family members and gankyrin, a liver oncoprotein. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.