Thermo Fisher Scientific LNK Polyclonal Antibody
Thermo Fisher Scientific의 LNK Polyclonal Antibody는 인간 LNK 단백질을 인식하는 토끼 IgG 항체로, WB 및 ICC/IF에 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, 비결합형 액상 형태로 제공됩니다. 세포 신호전달 및 혈액학 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- View 1 publication
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LNK. Recombinant protein control fragment (Product #RP-102117) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643416 |
Product Specific Information
Immunogen sequence:
FDPPKSSRPK LQAACSSIQE VRRCTRLEMP DNLYTFVLKV KDRTDIIFEV GDEQQLNSWM AELSECTGRG LESTEAEMHI PSALEPSTSS SPRGSTDSLN QGASPGGLLD PACQKTDHFL SCYPWFH
Highest antigen sequence identity to the following orthologs:
- Mouse: 79%
- Rat: 77%
Target Information
This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors.
The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis.
Mutations in this gene have been associated with susceptibility to celiac disease type 13 and insulin-dependent diabetes mellitus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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