Thermo Fisher Scientific SEC31A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SEC31A. Recombinant protein control fragment (Product #RP-89208). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SEC31A,uniProtId:O94979-1,ncbiNodeId:9606,antigenRange:648-783,antigenLength:1220,antigenImageFileName:PA5-52147_SEC31A_O94979-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52147_SEC31A_O94979-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647080

Product Specific Information

Immunogen sequence: NWREALAAVL TYAKPDEFSA LCDLLGTRLE NEGDSLLQTQ ACLCYICAGN VEKLVACWTK AQDGSHPLSL QDLIEKVVIL RKAVQLTQAM DTSTVGVLLA AKMSQYANLL AAQGSIAAAL AFLPDNTNQP NIMQLR

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%.

Target Information

The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII, in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.