Thermo Fisher Scientific CRP Monoclonal Antibody (C2)
인간 CRP 단백질을 인식하는 Mouse monoclonal antibody (Clone C2). IHC(P) 및 ELISA에 사용 가능하며, Ca2+ 존재 여부와 관계없이 항원을 인식. 단백질 A로 정제된 액상 형태, 4°C 보관, 연구용 전용.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C2 |
| Immunogen | Purified human CRP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11155416 |
Product Specific Information
This antibody recognizes the antigen both in the presence and in the absence (samples containing EDTA) of Ca²⁺.
Target Information
C-reactive protein (CRP) is a major cyclic, pentameric acute phase protein composed of five identical, noncovalently bound, nonglycosylated subunits. Each subunit consists of 206 amino acids with a molecular weight of approximately 24 kDa. CRP is synthesized by the liver, and plasma levels increase markedly during inflammation. It initiates the classical complement cascade, binds to nuclear components such as chromatin and histones, and plays a key role in innate immunity and host defense. CRP levels can increase 100–1000 fold in response to injury, infection, or inflammation. Elevated basal CRP levels are associated with increased risk of hypertension and cardiovascular disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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