Thermo Fisher Scientific CRP Monoclonal Antibody (C5)
CRP 단백질을 인식하는 마우스 단클론 항체(C5 클론). Western blot 및 ELISA에 사용 가능하며, 칼슘 존재 여부와 무관하게 항원 인식. 단백질 A로 정제된 액상 형태, 4°C 보관. 염증 및 면역 반응 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: Not specified
- View 1 publication
ELISA
- Assay-dependent
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C5 |
| Immunogen | Purified human CRP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152143 |
Product Specific Information
This antibody recognizes antigen both in the presence and absence of Ca²⁺ (including samples containing EDTA).
Target Information
C-reactive protein (CRP) is a major cyclic, pentameric acute phase protein consisting of five identical, noncovalently bound, nonglycosylated subunits. Each subunit has 206 amino acids and a molecular weight of approximately 24 kDa.
CRP is synthesized by the liver and its plasma concentration increases markedly during inflammation. It initiates the classical complement cascade, binds to nuclear components such as chromatin and histones, and plays a key role in innate immunity.
CRP acts as an opsonin, activates monocytes/macrophages, and functions as a scavenger during cell necrosis. Elevated CRP levels are associated with increased risk of hypertension and cardiovascular disease.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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