Thermo Fisher Scientific WSB1 Polyclonal Antibody
Thermo Fisher Scientific의 WSB1 폴리클로날 항체는 인간 WSB1 단백질을 인식하며 WB, IHC, ELISA 등에 사용됩니다. 고순도 항원 친화 크로마토그래피로 정제되었고, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.0–2.0 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | WSB1 antibody for a 16 amino acid peptide near the amino terminus of human WSB1 (within amino acids 70–120 of WSB1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718713 |
Target Information
WSB1 (WD repeat and SOCS box-containing 1), also known as SWIP1, is a 421 amino acid protein containing one SOCS box domain and six WD repeats. It is expressed as multiple alternatively spliced isoforms and functions as part of an SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex, mediating ubiquitination and proteasomal degradation of target proteins such as DIO2. Overexpression of WSB1 is implicated in pancreatic cancer progression, suggesting a role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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