Thermo Fisher Scientific TRPM5 Polyclonal Antibody
Zebrafish TRPM5 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. 동결건조 형태로 제공되며, 재구성 후 사용. TRPM5의 칼슘 활성화 비선택적 양이온 채널 연구에 적합. 연구용으로만 사용.
- 카탈로그번호
- OST00076G-500UG
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 10–50 µg/mL |
| Immunohistochemistry (IHC) | 10–50 µg/mL |
| Miscellaneous PubMed (Misc) | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Zebrafish |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from zebrafish TRPM5, conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TRPM5.
Target Information
The TRPM5 gene encodes a member of the transient receptor potential (TRP) protein family, a diverse group of ion channel proteins.
This protein plays a key role in taste transduction and functions as a calcium-activated, non-selective cation channel that conducts Na⁺, K⁺, and Cs⁺ ions but not Ca²⁺ ions.
It is activated by low intracellular Ca²⁺ concentrations and inhibited by higher levels.
TRPM5 is also temperature-sensitive, showing increased inward currents between 15–35°C.
The gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5 and is imprinted, expressed only from the paternal allele.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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