Thermo Fisher Scientific TRPM5 Polyclonal Antibody
Zebrafish TRPM5 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC에 사용 가능. Lyophilized 형태로 제공되며, 4°C 또는 -20°C에서 보관. Taste transduction 관련 연구용으로 적합.
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- OST00075W-100UL
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Zebrafish |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from zebrafish TRPM5, conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: TRPM5.
Target Information
This gene encodes a member of the transient receptor potential protein family, which is a diverse group of proteins with structural features typical of ion channels.
TRPM5 plays an important role in taste transduction and functions as a calcium-activated, non-selective cation channel that carries Na⁺, K⁺, and Cs⁺ ions equally well, but not Ca²⁺ ions.
It is activated by lower concentrations of intracellular calcium and inhibited by higher concentrations.
TRPM5 is also highly temperature-sensitive, showing a steep increase of inward currents between 15°C and 35°C.
The gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5 and is imprinted, with exclusive expression from the paternal allele.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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