Thermo Fisher Scientific TRPC5 Polyclonal Antibody
TRPC5 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 제브라피쉬 반응성을 가지며, 무보존제 전체 혈청 형태로 제공됩니다. 연구용으로만 사용되며 장기 보관 시 -20°C 권장됩니다.
- 카탈로그번호
- OST00073W-100UL
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:300–1:3,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:300–1:3,000
Miscellaneous PubMed (Misc)
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Zebrafish |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide as a part of zebrafish TRPC5, conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TRPC5.
Target Information
TRPC5 belongs to the transient receptor family and is one of seven mammalian TRPC (transient receptor potential channel) proteins.
It is a multi-pass membrane protein forming receptor-activated non-selective calcium permeant cation channels.
TRPC5 functions alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4.
It interacts with multiple proteins including calmodulin, CABP1, enkurin, NHERF, MX1, RNF24, and SESTD1.
TRPC5 channels are operated by phosphatidylinositol second messenger systems activated by receptor tyrosine kinases or G-protein coupled receptors.
It may also be activated by intracellular calcium store depletion.
Diseases associated with TRPC5 include Hypertrophic Pyloric Stenosis and Pyloric Stenosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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