Thermo Fisher Scientific TRPC5 Polyclonal Antibody
Zebrafish TRPC5 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. 합성 펩타이드 면역원으로 제작되었으며, Lyophilized 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Zebrafish |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from zebrafish TRPC5, conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TRPC5.
Target Information
TRPC5 belongs to the transient receptor family and is one of seven mammalian TRPC (transient receptor potential channel) proteins.
This multi-pass membrane protein forms a receptor-activated, non-selective calcium-permeant cation channel.
TRPC5 can act alone or as a heteromultimer with TRPC1, TRPC3, and TRPC4.
It interacts with proteins such as calmodulin, CABP1, enkurin, NHERF, MX1, RNF24, and SESTD1.
TRPC5 activity is regulated by phosphatidylinositol second messenger systems activated by receptor tyrosine kinases or G-protein coupled receptors, and may also respond to intracellular calcium store depletion.
Diseases associated with TRPC5 include Hypertrophic Pyloric Stenosis and Pyloric Stenosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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