Thermo Fisher Scientific CTLA4 Monoclonal Antibody (OTI6F1)
인간 CTLA4 단백질을 인식하는 Mouse IgG1 단클론 항체. Flow Cytometry에 적합하며, 무보존제 PBS 용액에 동결건조 형태로 제공. 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Flow Cytometry (Flow) | 1:400 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6F1 |
| Immunogen | Full length human recombinant protein of human CTLA4 (NP_005205) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor primarily expressed on CD4+ T cells.
It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells) with higher affinity, but unlike CD28, CTLA4 inhibits T cell activation and function.
Intracellular CTLA4 is also found in regulatory T cells and may play a key role in their suppressive function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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