Thermo Fisher Scientific alpha Galactosidase Polyclonal Antibody
Human alpha Galactosidase 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:500~1:1,000 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol 버퍼에 보관. Fabry 질환 관련 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human alpha Galactosidase. Recombinant protein control fragment (Product #RP-91934) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637881 |
Product Specific Information
Immunogen sequence:
HISPQAKALL QDKDVIAINQ DPLGKQGYQL RQGDNFEVWE RPLSGLAWAV AMINRQEIGG PRSYTIAVAS LGKGVACNPA CFITQLLPVK RKLGFYEWTS RLRSHINPTG T
Highest antigen sequence identity to orthologs:
- Mouse: 70%
- Rat: 69%
Target Information
This gene encodes a homodimeric glycoprotein that hydrolyzes the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. The enzyme predominantly hydrolyzes ceramide trihexoside and catalyzes the hydrolysis of melibiose into galactose and glucose.
Mutations in this gene cause Fabry disease, a rare lysosomal storage disorder due to failure to catabolize alpha-D-galactosyl glycolipid moieties.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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