Thermo Fisher Scientific OTC Polyclonal Antibody
Thermo Fisher Scientific의 OTC Polyclonal Antibody는 인간 OTC 단백질을 인식하는 토끼 다클론 항체로, Western blot, IHC, ICC/IF에 적합합니다. 고순도 항원 친화 크로마토그래피 정제, 안정적 액상 포맷, 연구용으로 신뢰성 높은 결과를 제공합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:5,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human OTC. Recombinant protein control fragment (Product #RP-91882). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645101 |
Product Specific Information
Immunogen sequence:
ILADYLTLQE HYSSLKGLTL SWIGDGNNIL HSIMMSAAKF GMHLQAATPK GYEPDASVTK LAEQYAKENG TKLLLTNDPL EAAHGGNVLI TDTWISMGQE EEKKKRLQAF QGYQVTMKTA KVAASDWT
Highest antigen sequence identity:
- Mouse: 93%
- Rat: 92%
Target Information
This nuclear gene encodes a mitochondrial matrix enzyme. Mutations in this enzyme (missense, nonsense, frameshift) cause ornithine transcarbamylase deficiency, leading to hyperammonemia. The gene’s proximity to that for Duchenne muscular dystrophy suggests possible relevance to that disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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