Thermo Fisher Scientific FABP7 Polyclonal Antibody
FABP7 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 신경 발달 및 종양 연구에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human FABP7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2720404 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is greater than 95% (by SDS-PAGE).
Target Information
FABP7 was initially isolated from a human fetal brain cDNA library. Its mRNA is expressed in adult brain and muscle tissues at low levels. The protein encoded by this gene belongs to the fatty acid binding protein (FABPs) family—small, highly conserved cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism.
FABP7 is a downstream gene of the Pax6 transcription factor and is essential for maintaining neuroepithelial cells during early cortical development. It is frequently expressed in melanomas, and its down-regulation through RNAi can reduce cell proliferation and invasion, suggesting potential diagnostic and therapeutic applications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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