Thermo Fisher Scientific MMP7 Monoclonal Antibody (OTI4H8), TrueMAB
MMP7 단백질을 인식하는 Mouse monoclonal antibody로, Western blot과 IHC(P)에서 사용 가능. Human 시료에 반응하며, Lyophilized 형태로 제공. 재구성 후 약 1 mg/mL 농도로 사용 가능. 연구용으로 적합.
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 95–267 of human MMP7 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Matrix metalloproteinases (MMPs) are involved in extracellular matrix degradation during physiological processes such as development, reproduction, and tissue remodeling, as well as in pathological conditions like arthritis and metastasis.
MMP7 degrades proteoglycans, fibronectin, elastin, and casein, and differs from most MMPs by lacking a conserved C-terminal domain. It plays a role in wound healing and regulation of defensin activity in intestinal mucosa.
The MMP7 gene is located on chromosome 11q22.3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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