Thermo Fisher Scientific Phospho-Btk (Tyr551) Recombinant Rabbit Monoclonal Antibody (BtkY551-G12)
Human BTK 단백질의 Tyr551 인산화 부위를 인식하는 recombinant rabbit monoclonal antibody. Flow Cytometry 및 ELISA에 사용 가능. 높은 특이성과 재현성을 제공하며, Protein A/G로 정제된 액상 형태로 제공됨. 연구용으로만 사용.
- 카탈로그번호
- MA537120
- 판매단위
- pk
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–1,000 ng/mL
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BtkY551-G12 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr551 of human phospho Btk |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.10% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897054 |
Available Conjugated Formats
Target Information
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily. Mutations in the BTK gene are associated with developmental blocks in human B-cell ontogeny and immunodeficiency disorders. BTK interacts with toll-like receptors (TLR4, 6, 8, and 9), which are critical for innate and adaptive immunity. It also interacts with MyD88, TIRAP, and IRAK, but not TRAF-6, indicating a role in lipopolysaccharide signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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