Thermo Fisher Scientific PARP1 (cleaved Asp214) Recombinant Rabbit Monoclonal Antibody (PARP-H8), APC

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

5 µL/1x10^6 cells

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

PARP-H8

Immunogen

A synthetic peptide corresponding to residues surrounding Asp214 of human PARP. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PARP1 (cleaved Asp214),uniProtId:P09874-1,ncbiNodeId:9606,antigenRange:214,antigenLength:1014,antigenImageFileName:MA5-37115_PARP1_cleaved_Asp214_P09874-1_Rabbit.svg,antigenImageFileNamePDP:MA5-37115_PARP1_cleaved_Asp214_P09874-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

APC APC APC

View additional formats

• Unconjugated
• FITC
• PE
• Request custom conjugation

Excitation/Emission Max

651/660 nm View spectra

Form

Liquid

Purification

Protein A/G

Storage buffer

PBS with 0.20% BSA

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2897049

Target Information

Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.