
Thermo Fisher Scientific Phospho-GRK1/GRK2 (Tyr13) Polyclonal Antibody
GRK1/GRK2의 Tyr13 인산화 부위를 인식하는 Rabbit Polyclonal Antibody로 시각 신호전달 연구에 적합함. Western blot에서 1:1,000~1:3,000 희석으로 사용 가능. 액상형, 비결합(Unconjugated), -20°C 보관.
- 카탈로그번호
- PA5106088
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GRK1/2 around the phosphorylation site of Tyr13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817487 |
Target Information
The sensation of sight is the result of a cascade of events starting with the interaction of photoactivated rhodopsin with a protein called transducin.
Rhodopsin kinase, also known as GRK1, is a G-protein-coupled Ser/Thr kinase that regulates this cascade.
Following phosphorylation by GRK1, arrestin binds to phospho-rhodopsin, preventing further interaction with transducin and thereby quenching phototransductive activity.
By interrupting the phototransduction cycle, GRK1 plays a crucial role in resetting the visual system for subsequent events.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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