Thermo Fisher Scientific Phospho-HDAC7 (Ser486) Polyclonal Antibody
HDAC7의 Ser486 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal 항체. Western blot 및 Immunocytochemistry에 적합. 인간 및 생쥐 반응성. 1 mg/mL 액상 형태로 제공되며, PBS 및 glycerol buffer에 보관. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HDAC7 (Accession Q8WUI4), corresponding to amino acid residues around phosphorylated Ser486 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817489 |
Product Specific Information
Antibody detects endogenous levels of HDAC7 only when phosphorylated at Ser486.
Target Information
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events.
Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.
The protein encoded by this gene has sequence homology to members of the histone deacetylase family.
This gene is orthologous to the mouse HDAC7 gene, whose protein promotes repression mediated via the transcriptional corepressor SMRT.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-106090_HDAC7_Q8WUI4-1_Rabbit_PDP.jpeg)
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