Thermo Fisher Scientific Phospho-HtrA2 (Ser142) Polyclonal Antibody
인간 HtrA2 단백질의 Ser142 인산화 부위를 인식하는 Rabbit Polyclonal Antibody입니다. Western blot에 최적화되어 있으며, 고순도 액상 형태로 제공됩니다. 세포 사멸 관련 연구용으로 적합하며, -20°C에서 안정적으로 보관 가능합니다.
- 카탈로그번호
- PA5106092
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-HtrA2 (Ser142) Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HtrA2 around the phosphorylation site of Ser142 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817491 |
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity.
Recently, a serine protease called Omi/HtrA2 has been identified, which is released from mitochondria upon induction of apoptosis. This mitochondrial protein binds to IAPs. Like Smac/DIABLO, the mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus.
Deregulated expression of Omi in the cytoplasm of mammalian cells induces apoptosis, suggesting that Omi participates in the mitochondrial apoptotic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-106092_HTRA2_O43464-1_Rabbit.svg, PA5-106092_HTRA2_O43464-1_Rabbit_PDP.jpeg)
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