Thermo Fisher Scientific CD148 Monoclonal Antibody (MEM-CD148/05)
CD148 단백질의 세포외 에피토프를 인식하는 mouse IgG2b 단일클론 항체. 인간 시료 반응성으로 Flow Cytometry에 적합. Protein A 정제, PBS(pH 7.4) 버퍼 및 sodium azide 포함. 4°C 보관, 동결 금지. 연구용으로만 사용.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-CD148/05 |
| Immunogen | Human recombinant CD148 (amino acids 1–444) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745551 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope of CD148, a highly glycosylated receptor-like protein tyrosine phosphatase (up to 250 kDa) expressed mainly in lymphocytes, myeloid cells, and epithelial cells.
Target Information
CD148 is a highly glycosylated transmembrane protein of up to 250 kDa, containing eight fibronectin type III domains in the extracellular region and one tyrosine phosphatase domain in the cytoplasmic region.
Expression is found on fibroblasts, epithelial cells, lymphocytes (B, T, and NK cells), and myeloid cells (monocytes and granulocytes).
CD148 can dephosphorylate proteins such as LAT and PLC-gamma and is involved in the downregulation of T cell activation. Conversely, CD148 expression can be upregulated following T cell activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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