Thermo Fisher Scientific DVL2 Monoclonal Antibody (OTI2E11), TrueMAB
Human DVL2 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western Blot 및 IHC(P) 응용에 적합. Lyophilized 형태로 제공되며, PBS 및 trehalose buffer 포함. 연구용으로 Wnt 신호전달 관련 단백질 분석에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–320 of human DVL2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Disheveled DVL2 is a member of the dishevelled (dsh) protein family. Vertebrate dsh proteins share approximately 40% amino acid sequence similarity with Drosophila dsh.
This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the Wnt-mediated signal transduction pathway.
The mechanisms of dishevelled function in Wnt signaling are likely conserved among metazoans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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