Thermo Fisher Scientific Phospho-VEGF Receptor 1 (Tyr1213) Polyclonal Antibody
VEGFR1의 Tyr1213 인산화 형태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 액상 형태로 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-VEGF Receptor 1 (Tyr1213) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FLT1 (Accession P17948), corresponding to amino acid residues around phosphorylated Tyr1213. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818295 |
Product Specific Information
This antibody detects endogenous levels of VEGFR1 only when phosphorylated at Tyrosine 1213.
Target Information
FLT1 (VEGFR1) is a receptor tyrosine kinase that plays a critical role in angiogenesis. Active angiogenesis is involved in various physiological and pathological processes such as tumor progression, diabetic retinopathy, rheumatoid arthritis, and wound healing.
FLT1 may act as a negative regulator of embryonic angiogenesis by inhibiting excessive endothelial cell proliferation, while promoting endothelial cell proliferation and angiogenesis in adulthood in a cell-type specific manner.
It has high affinity for VEGFA but relatively low kinase activity, possibly functioning as a negative regulator of VEGFA signaling by limiting free VEGFA availability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.