Thermo Fisher Scientific COL1A1 Polyclonal Antibody
COL1A1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. 인체 및 설치류 시료에서 반응하며, 고순도 Affinity Chromatography로 정제된 액상 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | 1 publication |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| ELISA | 1 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Rat, Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1151–1250 of human Collagen I/COL1A1 (NP_000079.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805466 |
Product Specific Information
- Positive Samples: Mouse spleen, Mouse kidney, Rat liver, Rat lung
- Cellular Location: Extracellular matrix, extracellular space
- Immunogen Sequence:
PGKDGLNGLP GPIGPPGPRG RTGDAGPVGP PGPPGPPGPP GPPSAGFDFS FLPQPPQEKA HDGGRYYRAD DANVVRDRDL EVDTTLKSLS QQIENIRSPE G
Target Information
The protein encoded by this gene is the pro-alpha1 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis, and tendon.
Mutations in this gene are associated with osteogenesis imperfecta types I–IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease, and idiopathic osteoporosis.
Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with dermatofibrosarcoma protuberans, resulting from unregulated growth factor expression.
Two transcripts, resulting from alternate polyadenylation signals, have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-89281_COL1A1_P02452-1_Rabbit.svg)
(이미지: PA5-89281_COL1A1_P02452-1_Rabbit_PDP.jpeg)
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