Thermo Fisher Scientific HYD Polyclonal Antibody
Thermo Fisher Scientific의 HYD Polyclonal Antibody는 인간 UBR5 단백질(aa 550-760)에 특이적인 토끼 IgG 항체로, Western blot 및 ELISA에 적합합니다. 액상 형태로 제공되며, 높은 순도의 Affinity Chromatography 정제 제품입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 550–760 of human UBR5 (NP_0569862) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.92 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805582 |
Product Specific Information
- Immunogen sequence: SISAGIPKVG VLMESVWNMN DSCRFQLRSP ESLKNMEKAS KTTEAKPESK QEPVKTEMGP PPSPASTCSD ASSIASSASM PYKRRRSTPA PKEEEKVNEE QWSLREVVFV EDVKNVPVGK VLKVDGAYVA VKFPGTSSNT NCQNSSGPDA DPSSLLQDCR LLRIDELQVV KTGGTPKVPD CFQRTPKKLC IPEKTEILAV NVDSKGVHAV L
- Positive Samples: U-87MG, 293T, Jurkat, HeLa
- Cellular Location: Nucleus
Target Information
EDD (E3 identified by Differential Display) is a progestin-regulated gene isolated from T-47D human breast cancer cells. Based on sequence homology, EDD appears to be a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor gene required for imaginal disc growth control.
EDD contains a HECT domain in the carboxy terminus. HECT domain-containing proteins function as ubiquitin-protein ligases (E3 enzymes). EDD binds to ubiquitin and may function as an E3 ubiquitin-protein ligase.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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