Thermo Fisher Scientific ZMYM4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 35-230 of human ZMYM4 (NP_0050862) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZMYM4,uniProtId:Q5VZL5-1,ncbiNodeId:9606,antigenRange:35-230,antigenLength:1548,antigenImageFileName:PA5-89455_ZMYM4_Q5VZL5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89455_ZMYM4_Q5VZL5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.44 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805579

Product Specific Information

Immunogen sequence: TEMSEDIDHN LTPTLDSMSY GMPNQTGSEN SLLDEDDYFL NSGDLAGIPV VGSDNEDEQD FSSKDNLVSS IHTDDSLEVE RRVTQHESDN ENEIQIQNKL KKDFPKQFDQ VSVFKSIRKD FSLVRENSKE TFSGKEKNRD LTYEREKRLD KPHKDLDSRL KSSFFDKAAN QVEETLHTHL PQTPETNFRD SSYPFA; Positive Samples: 293T, HepG2, U87, HeLa

Target Information

Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. It has been found to be overexpressed in human lung adenocarcinomas and squamous cell carcinomas, and the overexpression of a fragment of the 3`UTR of the ZMYM4 mRNA termed Cell Death Inhibiting RNA (CDIR) protects HeLa cells from IFN-gamma-induced apoptosis, suggesting that ZMYM4 may play a role in tumorigenesis.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.