Thermo Fisher Scientific MMP27 Polyclonal Antibody
인간 MMP-27 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 완충액에 보관됩니다. 종양 침윤 및 세포외기질 분해 연구에 활용 가능합니다.
- 카탈로그번호
- PA125307
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the hinge domain of human MMP-27 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2146438 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Metalloproteinases (MMPs) are a family of proteins involved in the breakdown of the extracellular matrix during normal cellular events such as reproduction, tissue remodeling, and embryonic development.
MMPs play a crucial role in tumor invasion and metastasis formation due to their ability to degrade extracellular matrix proteins including fibronectin, laminin, gelatin, and collagen.
MMP-27 (matrix metallopeptidase 27) is a 513 amino acid secreted protein expressed in B-cells. It belongs to the peptidase M10A family and contains four hemopexin-like domains, which are suggested to be involved in substrate recognition.
MMP-27, along with other MMP family members, is associated with breast cancer development and tumor progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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