Thermo Fisher Scientific MMP25 Polyclonal Antibody
Human MMP25 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 50% glycerol buffer에 보관됩니다. 단기 4°C, 장기 -20°C에서 안정적으로 저장 가능합니다.
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Thermo Fisher Scientific MMP25 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the propeptide domain of human MMP-28 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2250863 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in extracellular matrix breakdown in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes like arthritis and metastasis.
Most MMPs are secreted as inactive proproteins activated by extracellular proteinases.
MMP25 belongs to the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor.
In response to bacterial infection or inflammation, MMP25 may inactivate alpha-1 proteinase inhibitor, promoting neutrophil migration to inflammatory sites.
It may also contribute to tumor invasion and metastasis through activation of MMP2.
The gene was previously referred to as MMP20 but has been renamed MMP25.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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