Thermo Fisher Scientific Steroidogenic Factor 1 (SF-1) Recombinant Rabbit Monoclonal Antibody (SF1/8000R)
Recombinant rabbit monoclonal antibody for SF-1 detection in human and rat samples. Suitable for IHC applications with high specificity and reproducibility. Expressed in HEK293 cells and purified via Protein A/G. Stable liquid form for research use only.
- 카탈로그번호
- 2516-RBM11-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Steroidogenic Factor 1 (SF-1) Recombinant Rabbit Monoclonal Antibody (SF1/8000R)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SF1/8000R |
| Immunogen | Recombinant fragment (around aa200–400) of human SF-1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. SF-1 is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland. It promotes transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family.
SF-1 contains two activation function domains (AF1 and AF2) common to nuclear steroid receptors, necessary for interaction with other nuclear receptors, coactivators, and corepressors such as:
- Steroid receptor coactivator-1 (SRC-1)
- Glucocorticoid receptor interacting protein 1 (GRIP1)
- cAMP response element binding protein (CREB) binding protein (CBP)
- Silencing mediator of retinoid acid and thyroid hormone receptor (SMRT)
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.