Thermo Fisher Scientific Steroidogenic Factor 1 (SF-1) Monoclonal Antibody (rNR5A1/4369)
SF-1 단백질을 인식하는 마우스 모노클로날 항체로 인간 및 랫트 시료에 반응합니다. 면역조직화학(IHC) 분석에 적합하며, Protein A/G로 정제된 액상 형태입니다. 스테로이드 생성 관련 연구용으로 사용됩니다.
- 카탈로그번호
- 2516-MSM9-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Steroidogenic Factor 1 (SF-1) Monoclonal Antibody (rNR5A1/4369)
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rNR5A1/4369 |
| Immunogen | Recombinant fragment (around aa220–461) of human SF-1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. SF-1 is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland. It promotes transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family. SF-1 contains two activation function domains (AF1 and AF2), which are necessary for interaction with other nuclear receptors, coactivators, and corepressors such as SRC-1, GRIP1, CREB binding protein (CBP), and SMRT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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