Thermo Fisher Scientific Steroidogenic Factor 1 (SF-1) Recombinant Rabbit Monoclonal Antibody (SF1/8000R)
Recombinant rabbit monoclonal antibody targeting SF-1 for IHC applications. Reacts with human and rat. High specificity and reproducibility. Supplied as liquid, 1 mg/mL in PBS without preservative. For research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SF1/8000R |
| Immunogen | Recombinant fragment (around aa200–400) of human SF-1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in the development and differentiation of the endocrine system. It is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland. SF-1 promotes transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family.
It contains two activation function domains (AF1 and AF2), common to nuclear steroid receptors, required for interaction with coactivators and corepressors such as SRC-1, GRIP1, CBP, and SMRT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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