Thermo Fisher Scientific Steroidogenic Factor 1 (SF-1) Recombinant Rabbit Monoclonal Antibody (SF1/8150R)
SF-1 단백질을 표적하는 Thermo Fisher의 재조합 토끼 모노클로날 항체로 인간과 랫트 시료에 반응합니다. IHC(P) 및 IHC(PFA) 응용에 적합하며, 고순도 Protein A/G 정제 방식으로 제조되었습니다. 4°C에서 보관하며 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SF1/8150R |
| Immunogen | Recombinant fragment (around aa200–400) of human SF-1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. SF-1 is essential for fetal development of the hypothalamus, pituitary gland, gonads, and adrenal gland. It promotes transcriptional activity of steroidogenic enzymes from the cytochrome P450 family. SF-1 contains two activation function domains (AF1 and AF2), necessary for interactions with nuclear receptors, coactivators, and corepressors such as SRC-1, GRIP1, CREB binding protein (CBP), and SMRT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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