Thermo Fisher Scientific CD3d Recombinant Rabbit Monoclonal Antibody (JJ08-97)
Thermo Fisher Scientific의 CD3d 재조합 토끼 단클론 항체(JJ08-97)는 인간 CD3d 단백질을 표적으로 하며, WB, IHC, ICC/IF, Flow Cytometry 등에 사용 가능. 높은 특이성과 재현성을 제공하며, Protein A로 정제된 액상 형태로 공급됨. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JJ08-97 |
| Immunogen | Recombinant protein within Human CD3D aa 60–171 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809739 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, and individual clones are screened to select the best candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
CD3d is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and plays a role in T-cell development and signal transduction. It represents the delta subunit of the CD3 complex, which, together with other CD3 subunits, binds TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on T-cell surfaces.
Defects in the CD3d gene can cause severe combined immunodeficiency (SCIDBNK). Two transcript variants encoding different isoforms of CD3d have been identified; other variants may exist but are not fully defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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