Thermo Fisher Scientific DNMT1 Monoclonal Antibody (11H8), FITC
DNMT1 단백질 검출용 FITC 결합 단클론 항체. Western blot과 면역세포화학(ICC/IF)에 적합. 인간 DNMT1의 637-650 아미노산 서열을 면역원으로 제작. 1 mg/mL 액상 형태, 4°C 암소 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 11H8 |
| Immunogen | Synthetic peptide corresponding to amino acids 637–650 of human DNMT1 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
2 µg/mL of MA5-45336 was sufficient for detection of DNMT1 in 10 µg of mouse ES cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 180 kDa and cross-reacts with mouse DNMT1.
Target Information
This gene encodes a subunit of the augmin complex, which regulates centrosome and mitotic spindle integrity and is necessary for the completion of cytokinesis. The encoded protein interacts with ubiquitin C-terminal hydrolase 37. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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