Thermo Fisher Scientific CD2 Monoclonal Antibody (OTI3E11), TrueMAB
인간 CD2 단백질을 인식하는 mouse IgG1 단일클론 항체로, WB, IHC, Flow Cytometry에 사용 가능. Lyophilized 형태로 제공되며, PBS buffer와 trehalose 포함. 연구용으로 T-cell 표지 및 세포 접착 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E11 |
| Immunogen | Full length human recombinant protein of human CD2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CD2 (LFA-2) is a monomeric surface antigen (MW 45–58 kDa) expressed on human T-lymphocytes and some NK cells, but not on B lymphocytes. It plays a key role in T-cell adhesion and activation through interaction with CD58.
CD2 deficiency is associated with reduced intestinal inflammation and certain immune disorders. Diseases linked to CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to thymus absence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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