Thermo Fisher Scientific BAK Recombinant Rabbit Monoclonal Antibody (SU32-07)
인간 BAK 단백질을 인식하는 재조합 토끼 모노클로날 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 높은 특이성과 민감도, 로트 간 일관성 제공. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SU32-07 |
| Immunogen | Synthetic peptide within Human Bak (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809404 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
The protein encoded by this gene belongs to the BCL2 protein family. Members of this family form oligomers or heterodimers and act as anti- or pro-apoptotic regulators involved in diverse cellular activities. This protein localizes to mitochondria and induces apoptosis by interacting with mitochondrial channels, leading to cytochrome c release. It also interacts with tumor suppressor P53 under cell stress conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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