Thermo Fisher Scientific GDF1 Polyclonal Antibody
GDF1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 합성 펩타이드 면역원 사용, Affinity chromatography로 정제. PBS/glycerol buffer에 보관하며 -20°C에서 안정적.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GDF1 (Accession P27539), corresponding to amino acid residues A52–V102 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852434 |
Product Specific Information
This antibody detects endogenous levels of total GDF1.
Target Information
Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily involved in embryonic development and adult tissue homeostasis.
GDF1 was initially identified as a temporally expressed gene in the mouse central nervous system during embryonic development, with only one isoform detected in adult tissues.
GDF1 is required for left-right patterning during development and directly interacts with Nodal, another member of the TGF-beta superfamily. It has been suggested that GDF1 regulates the activity and signaling range of Nodal through direct interaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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