Thermo Fisher Scientific K-cadherin Monoclonal Antibody (2B6)
K-cadherin 단백질을 검출하는 Mouse IgG1 단일클론 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합. Human 및 Rat 시료 반응성 확인. 고순도 정제된 형태로 제공되며, 장기 보관 시 -20°C에서 안정적 유지.
- 카탈로그번호
- MA106305
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:25–1:250 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25–1:50 | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:25–1:50 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:25–1:50 | View publication |
| Neutralization (Neu) | – | View 1 publication |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B6 |
| Immunogen | Affinity purified extracellular domain of human cadherin-6-GST fusion protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2078120 |
Product Specific Information
MA1-06305 detects K-cadherin in human and rat samples.
It has been successfully used in Western blotting, immunocytochemistry, and immunohistochemistry (paraffin).
By Western blotting, it detects a ~120 kDa protein representing K-cadherin.
The immunogen is the affinity purified extracellular domain of human cadherin-6-GST fusion protein.
Store at 4ºC or in small aliquots at -20ºC.
Target Information
Cadherins are transmembrane glycoproteins involved in Ca²⁺-dependent cell-cell interactions.
They are differentially expressed in various tissues and contribute to tissue integrity and morphogenesis.
Cadherins are divided into:
- Type I: E-cadherin (cadherin-1), N-cadherin (cadherin-2), P-cadherin (cadherin-3), R-cadherin (cadherin-4)
- Type II: K-cadherin (cadherin-6), OB-cadherin (cadherin-11)
Cadherin-6 is expressed in the proximal tubule epithelium of the kidney, from which most renal cell carcinomas are derived.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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