Thermo Fisher Scientific K-cadherin Monoclonal Antibody (2B6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:25-1:250

View 1 publication 1 publication

Immunohistochemistry (IHC)

-

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:25-1:50

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

1:25-1:50

-

Immunocytochemistry (ICC/IF)

1:25-1:50

-

Neutralization (Neu)

-

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Rat

Published species

Human, Mouse

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

2B6

Immunogen

Affinity purified, extracellular domain of human cadherin-6-GST fusion protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

purified

Storage buffer

PBS

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2078120

Product Specific Information

MA1-06305 detects K-cadherin in human and rat samples.

MA1-06305 has sucessfully been used in Western blotting, immunocytochemistry, and immunohistochemistry (paraffin). By Western blotting, it detects a ~120 kDa protein representing K-cadherin.

The MA1-06305 immunogen is affinity purified extracellular domain of human cadherin-6-GST fusion protein.

Store at 4ºC or in small aliquots at -20ºC.

Target Information

Cadherins constitute a family of transmembrane glycoproteins involved in Ca2+-dependent cell-cell interactions. The members of this family are differentially expressed in various tissues. They function in the maintenance of tissue integrity and morphogenesis. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin, cadherin-1 or uvomorulin), neural cadherin (N-cadherin or cadherin-2), placental cadherin (P-cadherin or cadherin-3) and retinal cadherin (R-cadherin or cadherin-4), whereas kidney cadherin (K-cadherin or cadherin-6) and osteoblast cadherin (OB-cadherin or cadherin-11) are type II cadherins. Cadherin-6 is expressed in the proximal tubule epithelium of the kidney from which most renal cell carcinomas are derived.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.