Thermo Fisher Scientific alpha Galactosidase Polyclonal Antibody
Human alpha Galactosidase를 인식하는 Rabbit Polyclonal Antibody. IHC(P)에서 1:200–1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제. PBS, 40% glycerol, 0.02% sodium azide 포함. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human alpha Galactosidase. Recombinant protein control fragment (Product # RP-91935) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856031 |
Product Specific Information
Immunogen sequence:
FDGCYCDSLE NLADGYKHMS LALNRTGRSI VYSCEWPLYM WPFQKPNYTE IRQYCNHWRN FADIDDSWKS IKSILDWTSF NQERIVDVAG PGGWNDPDML VIGNFGLSWN QQVTQMA
Target Information
This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins.
This enzyme predominantly hydrolyzes ceramide trihexoside and catalyzes the hydrolysis of melibiose into galactose and glucose.
Mutations in this gene affect the synthesis, processing, and stability of this enzyme, causing Fabry disease—a rare lysosomal storage disorder resulting from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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