Thermo Fisher Scientific alpha Galactosidase Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human alpha Galactosidase. Recombinant protein control fragment (Product #RP-91935). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:alpha Galactosidase,uniProtId:P06280-1,ncbiNodeId:9606,antigenRange:169-285,antigenLength:429,antigenImageFileName:PA5-110620_alpha_Galactosidase_P06280-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110620_alpha_Galactosidase_P06280-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856031

Product Specific Information

Immunogen sequence: FDGCYCDSLE NLADGYKHMS LALNRTGRSI VYSCEWPLYM WPFQKPNYTE IRQYCNHWRN FADIDDSWKS IKSILDWTSF NQERIVDVAG PGGWNDPDML VIGNFGLSWN QQVTQMA

Target Information

This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.