
Thermo Fisher Scientific ACE2 Polyclonal Antibody
Thermo Fisher Scientific의 ACE2 Polyclonal Antibody는 인간 ACE2 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot 및 IHC(P) 검증 완료. 고순도 항원 친화 크로마토그래피 정제 제품으로 연구용 SARS-CoV-2 관련 ACE2 분석에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human ACE2. Recombinant protein control fragment (Product #RP-91894) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856024 |
Product Specific Information
Immunogen sequence:
MSSSSWLLLS LVAVTAAQST IEEQAKTFLD KFNHEAEDLF YQSSLASWNY NTNITEENVQ NMNNAGDKWS AFLKEQSTLA QMYPLQEIQN LTVKLQLQAL QQNGSSVLSE D
Target Information
Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. Unlike its homolog ACE, ACE2 expression is restricted to the heart, kidney, and testis. ACE2 is also a functional receptor of the SARS coronavirus. Its normal function is to convert Angiotensin I (AngI) to Ang1-9 and AngII to Ang1-7. Lack of ACE2 expression results in reduced cardiac contractility, indicating its importance in heart function regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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