Thermo Fisher Scientific GPR20 Polyclonal Antibody
Human GPR20 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 적용 검증 완료. 항원 친화 크로마토그래피로 정제된 액상형 시약이며, 4°C 단기 보관 및 -20°C 장기 보관 가능. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from N-terminal extracellular domain of human GPR20 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550278 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
- Human (100%)
- Gorilla, Monkey (95%)
- Marmoset (80%)
- For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, comprise a superfamily of proteins involved in diverse stimulus-response pathways.
GPR signaling is an ancient mechanism used by eukaryotes to sense environmental stimuli and mediate cell-cell communication.
GPR20 is a 358 amino acid membrane protein that constitutively activates G(i) proteins without ligand stimulation and may regulate intracellular cAMP levels and mitogenic signaling.
It is expressed in liver and certain brain regions (putamen, caudate, thalamus), but not in hypothalamus, pons, or frontal cortex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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