Thermo Fisher Scientific GPR22 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

20 µg/mL

-

Product Specifications

Species Reactivity

Bat, Bovine, Chicken, Horse, Hamster, Human, Mouse, Non-human primate, Pig, Rabbit, Rat, Xenopus, Zebrafish

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 16 amino acid peptide from C-terminal cytoplasmic domain of human GPR22. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GPR22,uniProtId:Q99680-1,ncbiNodeId:9606,antigenRange:433,antigenLength:433,antigenImageFileName:PA5-32818_GPR22_Q99680-1_Rabbit.svg,antigenImageFileNamePDP:PA5-32818_GPR22_Q99680-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2550280

Product Specific Information

Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Bat, Bovine, Hamster, Elephant, Panda, Horse, Rabbit, Pig, Turkey, Chicken, Lizard, Xenopus, Pufferfish, Zebrafish, Stickleback (100%).

For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1, 000 members and is the largest known class of molecular targets with proven therapeutic value. GPR22 is an orphan G-protein-coupled receptor, belonging to the class A rhodopsin-like GPCRs. GPR22 is highly expressed in several human brain regions, heart and coronary arteries. GPR22 expression is also observed in normal pancreas and in pancreatic, colorectal, prostate and liver cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.