Thermo Fisher Scientific CD28 Monoclonal Antibody (CD28.2), Functional Grade, eBioscience
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
16-0289-050 | - | Thermo Fisher Scientific 16-0289-050 CD28 Monoclonal Antibody (CD28.2), Functional Grade, eBioscience 50 mg pk | 재고문의 | pk | 23,284,000원 | - | 25,612,400원 | ||
16-0289-025 | - | Thermo Fisher Scientific 16-0289-025 CD28 Monoclonal Antibody (CD28.2), Functional Grade, eBioscience 25 mg pk | 재고문의 | pk | 13,972,000원 | - | 15,369,200원 | ||
16-0289-38 | - | Thermo Fisher Scientific 16-0289-38 CD28 Monoclonal Antibody (CD28.2), Functional Grade, eBioscience 5 mg pk | 재고문의 | pk | 4,660,000원 | - | 5,126,000원 | ||
16-0289-85 | - | Thermo Fisher Scientific 16-0289-85 CD28 Monoclonal Antibody (CD28.2), Functional Grade, eBioscience 500 ug pk | 재고문의 | pk | 577,000원 | - | 634,700원 | ||
16-0289-81 | - | Thermo Fisher Scientific 16-0289-81 CD28 Monoclonal Antibody (CD28.2), Functional Grade, eBioscience 50 ug pk | 재고문의 | pk | 198,000원 | - | 217,800원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
-
View 4 publications 4 publications
Flow Cytometry (Flow)
1 µg/test
View 50 publications 50 publications
ELISA (ELISA)
-
View 2 publications 2 publications
Functional Assay (Functional)
Assay-Dependent
View 34 publications 34 publications
T-Cell Activation (TCA)
-
View 4 publications 4 publications
Affinity Purification (AP)
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View 2 publications 2 publications
In vitro Assay (IV)
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View 6 publications 6 publications
Miscellaneous PubMed (Misc)
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View 9 publications 9 publications
Product Specifications
Species Reactivity
Human
Published species
Fruit fly, Human, Mouse
Host/Isotype
Mouse / IgG1, kappa
Recommended Isotype Control
Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Functional Grade, eBioscience™
Class
Monoclonal
Type
Antibody
Clone
CD28.2
Conjugate
Functional Grade Functional Grade Functional Grade
View additional formats
- Unconjugated
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Biotin
- Brilliant UV 395
- Brilliant UV 615
- Brilliant UV 737
- Brilliant Violet 480
- Brilliant Violet 650
- Brilliant Violet 786
- eFluor 450
- FITC
- NovaFluor Blue 610-70S
- NovaFluor Blue 660-120S
- NovaFluor Blue 690
- NovaFluor Red 710
- NovaFluor Red 725
- NovaFluor Red 755
- NovaFluor Yellow 660
- NovaFluor Yellow 755
- PE
- PE-Cyanine7
- PE-eFluor 610
- PerCP-Cyanine5.5
- Super Bright 436
- Super Bright 600
- Super Bright 645
- Request custom conjugation
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
no preservative
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2865687
Product Specific Information
Description: The CD28.2 monoclonal antibody reacts with the human CD28 molecule, a 44 kDa homodimer expressed by thymocytes, mature T cells and plasma cells. CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) and is a potent co-stimulator of T cells. Signaling through CD28 augments IL-2 and IL-2 receptor expression as well as cytotoxicity of CD3-activated T cells.
Applications Reported: The CD28.2 antibody has been reported for use in flow cytometric analysis. CD28.2 has also been reported in costimulation of T cells in in vitro functional assays.
Applications Tested: TheCD28.2 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Storage and handling: Use in a sterile environment.
Filtration: 0.2 µm post-manufacturing filtered.
Purity: Greater than 90%, as determined by SDS-PAGE.
Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.
Aggregation: Less than 10%, as determined by HPLC.
Target Information
CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. CD28 is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes. Moreover, CD28 is the critical T cell costimulatory receptor that provides the cell the important second activation signal by binding CD80 and CD86 which are expressed by antigen presenting cells. In addition to its co-stimulation role, CD28 functions by preventing T cells from entering an anergic-hyporesponsive state or from undergoing premature apoptotic cell death. In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28. In the thymus, CD28 expression is highest on immature CD3-, CD8+ and CD4+8+ cells, and on CD4-8- cells that express alpha/beta and gamma/delta TCR. The level of CD28 on mature CD4+ and CD8+ alpha/beta TCR+ thymocytes is two- to fourfold lower than on the immature cells. Diseases associated with CD28 dysfunction include mycosis fungiodes and Sezary`s Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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