Thermo Fisher Scientific TDRD3 Recombinant Human Monoclonal Antibody (RAB-C419)

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

ChIP assay (ChIP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Human / F(ab), kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

RAB-C419

Immunogen

This antibody was obtained by recombinant antibody (rAb) phage display recognizing TDRD3 protein under non-denaturing conditions.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Metal-chelate chromatography

Storage buffer

PBS

Contains

0.02% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

Product Specific Information

This antibody recognizes TDRD3 (Tudor domain-containing protein 3). It binds to a folded domain, amino acids 1-455. TDRD3 is a scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins.

Target Information

TDRD3 belongs to the tudor domain group of proteins, which are prevalent among proteins involved in RNA metabolism. TDRD3 is widely expressed and localizes predominantly in the cytoplasm. It is detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. Overexpression of TDRD3 in cells induces the formation of stress granules. Multiple isoforms of TDRD3 exist due to alternative splicing variants. In humans, the gene is located on chromosome 13.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.