Thermo Fisher Scientific CETP Monoclonal Antibody (ATM192)
인간 및 토끼 CETP 단백질 검출용 단클론 항체로 Western blot, ELISA, IF, IP 등에 적합. 비결합형 액상 형태이며 Protein A로 정제됨. CETP의 역콜레스테롤 운반 연구에 활용 가능.
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Thermo Fisher Scientific CETP Monoclonal Antibody (ATM192)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:20 | - |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
| Miscellaneous PubMed | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rabbit |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ATM192 |
| Immunogen | Synthetic peptide corresponding to residues C D(149) S G R V R T D A P D(159) of human CETP protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_325404 |
Product Specific Information
MA1-050 detects cholesteryl ester transfer protein (CETP) from human and rabbit tissues.
This antibody has been successfully used in Western blot, immunoprecipitation, immunofluorescence, and ELISA protocols.
By Western blot, it detects a doublet at approximately 70 kDa from human serum representing CETP.
It can also immunoprecipitate CETP activity from serum samples using protein G.
The immunogen is a synthetic peptide corresponding to residues C D(149) S G R V R T D A P D(159) of human CETP protein.
Target Information
High density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver.
This process, known as reverse cholesterol transport, helps maintain systemic cholesterol levels.
CETP mediates neutral lipid transfer activity in plasma across various species, accelerating lipid exchange between pro- and anti-atherogenic lipoprotein fractions.
Elevated CETP levels are associated with increased risk of coronary heart disease, making CETP a potential target for atherosclerosis prevention.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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