Thermo Fisher Scientific LPAP Polyclonal Antibody
LPAP 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. IHC, ICC/IF, Flow, ELISA 등 다양한 응용에 사용 가능하며, Protein A로 정제된 1 mg/mL 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human LPAP, amino acids 125–206 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MSK-1 is a mitogen and stress activated protein kinase-1 belonging to the AGC family of kinases, structurally related to the ribosomal p70 S6 kinase subfamily. It is activated by ERK1/2 and SAPK2/p38 MAP kinase and is required for phosphorylation of CREB, ATF1, H3, and HMG-14 in response to mitogen and stress. MSK-1 contains two kinase domains (N-terminal and C-terminal). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK-1 autophosphorylates on multiple sites including Ser212 and Ser376, which are essential for catalytic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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