Thermo Fisher Scientific EphB4 Polyclonal Antibody
EphB4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간·마우스·랫에서 반응. Western blot 및 IHC(P) 실험에 적합하며, 고순도 Affinity chromatography로 정제됨. 액상 형태로 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHB4 (Accession P54760), corresponding to amino acid residues Y581–R631 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818370 |
Product Specific Information
Antibody detects endogenous levels of total EPHB4.
Target Information
EPHB4 is a receptor tyrosine kinase belonging to the ephrin receptor family. Members of the Eph family are involved in diverse biological processes such as nervous system development, angiogenesis, and neural synapsis formation and maturation.
Ephrins are divided into two classes based on structure and sequence:
- Ephrin-A (EFNA): anchored to the membrane via glycosylphosphatidylinositol linkage
- Ephrin-B (EFNB): transmembrane proteins
Eph receptors are similarly divided into two groups based on extracellular domain sequence similarity and ligand affinity. Ephrin receptors constitute the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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