Thermo Fisher Scientific G protein beta 1/GNB1 Polyclonal Antibody
Thermo Fisher Scientific의 GNB1 폴리클로날 항체는 인간, 마우스, 랫트에 반응하며 다양한 면역분석(WB, IHC, ICC, ELISA)에 사용 가능. KLH 결합 합성 펩타이드(aa 21–120)를 면역원으로 제작. 고순도 Protein A 정제, 액상 형태로 안정적 보관(-20°C).
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human G protein beta 1, amino acids 21–120 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Vision involves the conversion of light into electrochemical signals that are processed by the retina and subsequently sent to and interpreted by the brain. The process begins when rhodopsin absorbs light within the retina, becoming catalytically active and activating transducin, a GTP-binding protein. Activated transducin promotes hydrolysis of cGMP by phosphodiesterase (PDE), reducing intracellular cGMP concentration and closing ion channels, leading to membrane hyperpolarization and signal transmission. Rhodopsin activity is believed to be shut off by phosphorylation followed by arrestin binding. Transducin subunit composition differs between photoreceptor cells—rod transducin (Trα, Tβ, Tγ) and cone transducin (Tcα, Tβ, Tγ)—which contributes to differing light sensitivities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: BS-3941R_GNB1_P62873-1_Rabbit.svg, BS-3941R_GNB1_P62873-1_Rabbit_PDP.jpeg)
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